主要科研成果

论文

1 Zhang H,Yang GL,Bao ZW,Jin YX,Wang JM,Chen J,Qian MR*（通讯作者），Stereoselective effects of fungicide difenoconazole and its four stereoisomers on gut barrier, microbiota, and glucolipid metabolism in male mice, Science of the Total Environment, 2022, 805, 150454

2 Qian MR,Wang JM,Ji XF,Yang, H,Tang B,Zhang H,Yang GL,Bao ZW,Jin YX, Ecotoxicology and Environmental Safety, 2021, 221, 112464

3 Wu SC,Ji XF,Wang JM,Wu HZ,Han JZ,Zhang H,Xu J,Qian MR*（通讯作者）, Fungicide bromuconazole has the potential to induce hepatotoxicity at the physiological, metabolomic and transcriptomic levels in rats, Environmetal Pollution, 2021, 280,116940

4 Zhang XM, Li ZG, Wu HZ, Wang JM, Zhao HY, Ji XF, Xu Y, Li R, Zhang H, Yang H, Qian MR*(通讯作者), High-throughput method based on a novel thin-film microextraction coating for determining macrolides and lincosamides in honey, Food Chemistry, 2021,346

5 Ji XF, Xu Y, Wang JM, Lyu WT, Li R, Tan SM, Xiao YP, Tang B, Yang H, Qian MR*（通讯作者），Multiresidue determination of antibiotics in ready-to-eat duck eggs marketed through e-commerce stores in China and subsequent assessment of dietary risks to consumers，Journal of Food Science, 2021,5(86): 2145-2162

6 Wang JM, Xu J, Ji XF, Wu HZ, Yang H, Zhang H, Zhang XM, Li ZG, Ni XL, Qian MR*(通讯作者), Determination of veterinary drug/pesticide residues in livestock and poultry excrement using selective accelerated solvent extraction and magnetic material purification combined with ultra-high-performance liquid chromatography-tandem mass spectrometry. Journal of Chromatography A, 2020, 1617.

2 Qian MR, Zhou DN, Wang QY, Gao JD, Li D, Li YH, Yang B*, A reliable, simple and cost-efficient TLC-HPLC method for simultaneously determining florfenicol and florfenicol amine in porcine urine: application to residue surveillance, Food Additives & Contaminants: Part A, 2019, 36(8): 1218–1227.

3 Qian MR, Zhang XM#, Zhao HY, Ji XF, Li XD, Wang JM, Wu HZ, Xu J, Li ZG*, A high-throughput screening method for determination of multi-antibiotics in animal feed, Journal of Separation Sciences, 2019,42:2968–2976.

4 Ji XF, Yang H, Wang JM, Zhou W, Wang XL, Qian MR*(通讯作者), Evaluation of tilmicosin contamination in eggs following its administration to laying hens and subsequent assessment of dietary risks to Chinese consumers, Journal of Food Science, 2019,84 (10).

5 Ji XF, Yang H, Wang JM, Li R, Xu J, Xiao YP, Tang B, Qian MR*(通讯作者)，Occurrence of deoxynivalenol (DON) in cereal-based food products marketed through e-commerce stores and an assessment of dietary exposure of Chinese consumers to DON, Food Control,2018，92:391-398.

6 Wu HZ, Tong JY, Wang JM, Ji XF, Li ZG, Qian MR*(通讯作者),Syringe cleanup with ultra-high-performance liquid chromatography/tandem mass spectrometry for nitroimidazoles and steroids detection in manure-based fertilizers, Journal of Separation Sciences, 2018,41: 3089-3096.

7 QianMR, Yang H, Li ZG, Liu YP, Wang JM, Wu HZ, Ji XF, Xu J, Detection of 13 mycotoxins in feed using modified QuEChERS with dispersive magnetic materials and UHPLC–MS/MS, Journal of Separation Science, 2018,41:756-764.

8 Xia W, Wang JM, Yang H, Zhang H, Yang B, Zeng YH, Xu J, Li ZG*, Qian MR*(通讯作者), Bioaccumulation and Distribution of Hexabromocy -clododecaneIsomers in Duck Tissues, Bulletin of Environmental Contamination and Toxicology, 2018, 100:754-759.

9 Lin CM, Zhang LJ, Zhang H, Wang Q, Zhu JH, Wang JM, Qian MR(通讯作者), Enantioselective degradation of Myclobutanil and Famoxadone in grape, Environmental Science and Pollution Research, 2018,25:2718-2725.

10 Wu HZ, Wang JM, Yang H, Li GQ, Zeng YH, Xia W, Li ZG*, Qian MR*(通讯作者),Development and application of an in-cell cleanup pressurized liquid extraction with ultra-high-performance liquid chromatography-tandem mass spectrometry to detect prohibited antiviral agents sensitively in livestock and poultry feces, Journal of Chromatography A, 2017,1488:10-16.

11 Ji XF, Li R, Yang H, Qi PP, Xiao YP, Qian MR*(通讯作者), Occurrence of patulin in various fruit products and dietary exposure assessment for consumers in China, Food Control, 2017,78:100-107.

12 Miao QC, Wang JM, Nie J, Wu HZ, Liu YP, Li ZG*, Qian MR*(通讯作者), Magnetic dispersive solid-phase extraction based on a novel adsorbent for the detection of triazole pesticide residues in honey by HPLC-MS/MS, Analytical Methods, 2016,8:5296-5303.

13 Wang JM, Lin H, Sun WC, Xia Y, Ma JW, Fu JR, Zhang ZL, Wu HZ, Qian MR*(通讯作者), Variations in the fate and biological effects of sulfamethoxazole, norfloxacin and doxycycline in different vegetable–soil systems following manure application, Journal of Hazardous materials, 2016,304:49-57.

14 Qian MR, Wu HZ, Wang JM, Zhang H, Zhang ZL, Zhang YZ, Lin H, Ma JW*, Occurrence of trace elements and antibiotics in manure-based fertilizers from the Zhejiang Province of China, Science of The Total Environment, 2016,559:174-181.

15 Wu HZ, Qian MR^#(共同第一), Wang JM, Zhang H, Ma JW, Li ZG*, Lee MR, Simultaneous determination of sulfonamides and metabolites in manure samples by one-step ultrasound/microwave-assisted solid–liquid–solid dispersive extraction and liquid chromatography–mass spectrometry, Analytical and Bioanalytical Chemistry, 2015,407:3545-3554.

16 Qian MR, Zhang H, Wu LQ, Jin N, Wang JM, Jiang KZ, Simultaneous determination of zearalenone and its derivatives in edible vegetable oil by gel permeation chromatography and gas chromatography–triple quadrupole mass spectrometry, Food Chemistry, 2015,166:23-28.

17 Zheng SL, Wu HZ, Li ZG, Wang JM, Zhang H, Qian MR(通讯作者), Ultrasound/microwave‐assisted solid–liquid–solid dispersive extraction with high‐performance liquid chromatography coupled to tandem mass spectrometry for the determination of neonicotinoid insecticides in Dendrobium officinale, Journal of Separation Science, 2015,38:121-127.

18 Wu SC, Yu M, Zhang H, Han JZ, Qian MR(通讯作者), Enantioselective Degradation of (2RS, 3RS)‐Paclobutrazol in Rat Liver Microsomes, Chirality, 2015,27:344-348.

19 Xu MF, Qian MR(通讯作者), Zhang H, Ma JW, Wang JM, Wu HZ, Simultaneous determination of florfenicol with its metabolite based on modified quick, easy, cheap, effective, rugged, and safe sample pretreatment and evaluation of their degradation behavior in agricultural soils, Journal of Separation Science, 2015,38:211-217.

20 Jiang KZ, Zhang NW, Zhang H, Wang JM, Qian MR(通讯作者), Investigation on the Gas-Phase Decomposition of Trichlorfon by GC-MS and Theoretical Calculation, PLoS One, 2015,10:e0121389.

科研项目

[1] 典型手性杀菌剂在葡萄种植业—家酿制酒过程中的立体选择性降解和迁移规律研究，国家自然科学基金项目青年基金，2016-2018，24万元，主持、结题

[2] 蔬菜样品中农药助剂残留水平的测定及调查，国家科技基础性工作专项课题，2013-2018，100万元，主持、结题

[3] 六溴环十二烷在鸭体内的立体选择性分布及代谢研究，浙江省自然基金，2014-2016，9万元，主持、结题

其他科研业绩等

1．浙江省科技进步奖二等奖：畜禽有机肥安全利用关键技术（2019年、排名第3）

2．中国分析测试协会科学技术奖三等奖: 基于色质谱联用技术的手性农药残留分析及选择性代谢研究（2016年，排名第5）

3．《NY/T 3167-2017有机肥中磺胺类药物含量的测定液相色谱-串联质谱法》（排名第一）

4．《NY/T 2821-2015蜂胶中咖啡酸苯乙酯的测定液相色谱-串联质谱法》（排名第一）

5.《NY/T 2067-2011土壤中13种磺酰脲类除草剂残留量的测定液相色谱串联质谱法》（排名第一）

6.国家发明专利：ZL 201910593507.5基于CB7的养殖用水中恩诺沙星的快速测定方法（排名第一）

7.国家发明专利：ZL 2016 1 0733654.4有机肥中喹诺酮类药物的测定方法及其样品预处理方法（排名第一）

8.国家发明专利：ZL 2014 1 0652559.2一种金刚烷胺人工半抗原、人工抗原及其制备方法和应用（排名第一）

9.国家发明专利：ZL 2020 1 0304652.X蜂蜜中大环内酯类抗生素的检测方法及其样品处理方法（排名第二）

10.国家发明专利：ZL 2014 1 0652826.6一种分泌抗金刚烷胺单克隆抗体的杂交瘤细胞株及其应用（排名第三）