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韩玉林博士，河南商丘人，青年教师，理学博士。 学习工作经历 2007.9-2012.6 中山大学理学学士 2012.9-2018.1 中国科学院上海有机化学研究所理学博士（导师：麻生明院士） 2018.1-2018.12 复旦大学助理研究员 2019.1-2021.7 美国纽约西奈山伊坎医学院博士后（合作导师：金坚教授） 2021.10- 浙江树人大学交叉科学研究院青年教师 博士期间从事过渡金属催化的手性联烯化合物的环化反应的研究；博士后期间主要从事表观遗传学修饰方向的研究，开发用于癌症治疗的组蛋白甲基化酶和DNA甲基化酶的选择性抑制剂和降解剂（PROTACs）。目前以第一作者在Org. Chem. Front.，Chem. Eur. J.，Chin. J. Chem.等发表了SCI论文5篇，以通讯作者发表SCI论文1篇，其中一区1篇，二区4篇，三区1篇，并参与完成SCI论文7篇。 目前的研究兴趣主要为：金属有机化学、药物化学和有机功能材料化学。 |
主要科研成果
1. A. Qin, Q. Zhang, H. Qian*,Y. Han*, S. Ma*, Rh-Catalyzed Kinetic Resolution-Based Enantioselective [4+2]-Cycloaddition-Isomerization of Allene-1,3-dienes.Chin. J. Chem.2021, 39,559 - 565. (Breaking Report)
2. Y. Han, Y. Zhao, S. Ma*, Rhodium‐Catalyzed Pauson–Khand‐Type Cyclization of 1,5‐Allene‐Alkynes: A Chirality Transfer Strategy for Optically Active Bicyclic Ketones.Chem. Eur. J.2019,25, 9529 - 9533.
3. Y. Han,A. Qin, S. Ma*, One Stone for Three Birds-Rhodium-Catalyzed Highly Diastereoselective Intramolecular [4+2] Cycloaddition of Optically Active Allene-1,3-dienes.Chin. J. Chem.2019,37, 486 - 496.
4. Y. Han,S. Ma*, Rhodium-catalyzed highly diastereoselective intramolecular [4+2] cycloaddition of 1,3-disubstituted allene-1,3-dienes.Org. Chem. Front.2018,5, 2680 - 2684.
5. Y. Han, X. Zhang*, Theoretical Studies of Allene Synthesis through Cadmium Iodide-Mediated Allenylation of Terminal Alkynes.Asian J. Org. Chem.2017,6, 1778 - 1782.
6. Y. Han, X. Tang, J. Cheng, S. Ma*, Indium(III) Triflate-Catalyzed Efficient Prins-Type Cyclization of -Allenols and Aldehydes.Adv. Synth. Catal.2016,358, 4019 - 4029.
7. X. Tang,Y. Han, S. Ma*, Cadmium Iodide Mediated Allenylation of Terminal Alkynes for the Synthesis of Methyl-Substituted Allenes.Org. Lett.2015,17, 1176 - 1179.
8. X. Tang, X. Huang, T. Cao,Y. Han, X. Jiang, W. Lin, Y. Tang, J. Zhang, Q. Yu, C. Fu, S. Ma*, CuBr2-catalyzed enantioselective routes to highly functionalized and naturally occurring allenesOrg. Chem. Front.2015,2, 688 - 691.
9. W. Lin, T. Cao, W. Fan,Y. Han, J. Kuang, H. Luo, B. Miao, X. Tang, Q. Yu, W. Yuan, J. Zhang, C. Zhu, S. Ma*,Enantioselective Double Manipulation of Tetrahydroisoquinolines with Terminal Alkynes and Aldehydes under Copper(I) Catalysis.Angew. Chem. Int. Ed.2014,53, 277 - 281.
